A SIMPLE MODEL FOR RAT PAW EDEMA, TIME-COURSE STUDY
نویسندگان
چکیده
منابع مشابه
A model for rat paw edema. I. Fitness of the model to some types of edema.
The mechanism involved in the inflammatory process has been investigated by many workers. Biochemical and histological studies into the mechanism have been the favorite procedures among these investigators. Some of them have attempted to elucidate the inflammatory mechanism from the standpoint of possible biogenic mediators such as histamine, 5-hydroxytryptamine, bradykinin and proteases. Altho...
متن کاملTwo-Stage Nerve Graft in Severe Scar: A Time-Course Study in a Rat Model
excessive scarring; paralleling the process in tendon reconstruction of the hand. Inspired by the advantages of the two-stage technique in tendon grafting and with encouraging preliminary results, we aimed to investigate the two-stage nerve grafting technique as an alternative method of secondary nerve repair. Methods: Thirty female rats (~200 g) were randomly distributed into two groups (n=15...
متن کاملAn accurate and simple method for measurement of paw edema.
Several methods for measuring inflammation are available that rely on the parameters changing during inflammation. The most commonly used methods estimate the volume of edema formed. In this study, we present a novel method for measuring the volume of pathologically or artificially induced edema. In this model, a liquid column is placed on a balance. When an object is immersed, the liquid appli...
متن کاملThe anti-inflammatory effects of venlafaxine in the rat model of carrageenan-induced paw edema
Objective(s):Recently anti-inflammatory effects of antidepressants have been demonstrated. Venlafaxine belongs to newer antidepressants with serotonin norepinephrine reuptake inhibition property. The pain alleviating properties of venlafaxine in different pain models such as neurogenic pain, diabetic neuropathy, and fibromyalgia have been demonstrated. Anti-inflammatory effects of venlafaxine a...
متن کاملA model for rat paw edema. II. Analyses on the effect of the antagonists.
Making use of mathematical model we have attempted to classify the various agents modifying the rat paw edema. In the preceding paper (2) we described a model , which showed fairly good fitness to some selected cases of experimental edema in rats . The model is constructed on an assumption that the swelling volume is the reflection of the dynamic balance between the swelling force evoked by the...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1969
ISSN: 0021-5198
DOI: 10.1254/jjp.19.323